The role of microbes in health and disease

first_imgA new phase of the Human Microbiome Project (HMP)—which over the past five years identified the millions of microorganisms living on, and in, the human body—will focus on the roles played by these microbes both in health and disease. The new three-year “multi-omic” study at the Broad Institute of Harvard and MIT is being co-led by Curtis Huttenhower, associate professor of computational biology and bioinformatics in the Department of Biostatistics at HSPH and an associate member at the Broad.Under the new phase of the HMP, the Broad team will partner with 10 other institutions, including HSPH, to study the microbiomes of healthy people and those with inflammatory bowel disease (IBD)—a set of conditions including Crohn’s disease and ulcerative colitis—with a variety of “omics” techniques, such as proteomic, metabolomics, or transcriptomic analyses. These techniques will help the scientists understand how the microorganisms’ genes operate in disease, and could one day lead to new approaches for managing IBD.“In this phase, we specifically want to understand the biomolecular activity that’s occurring over time, which will require connecting many different data types into network models that capture microbial regulation and metabolism, and their effects on host cells and disease outcome,” said Huttenhower in a November 6, 2013 article on the Broad Institute’s website. Read Full Storylast_img read more

Asia’s World Cup qualifiers postponed to 2021 due to COVID-19

first_imgQualifying matches in Asia for the 2022 Qatar World Cup have been postponed until next year due to the coronavirus pandemic, world governing body FIFA and the Asian Football Confederation said in a statement on Wednesday.The second round of Asian qualifiers were originally scheduled to take place during the international windows in October and November but they would not go ahead due to the “COVID-19 situation in many countries”.It marks the second time the qualifiers, which also serve as the road to the 2023 Asian Cup in China, have been pushed back as matches in March and June were also postponed due to the pandemic. “With the aim of protecting the health and safety of all participants, FIFA and the AFC will continue to work together to closely monitor the situation in the region and to identify new dates for the respective qualifying matches,” the statement said.”Further details on the new dates for the next round of qualifying matches for the FIFA World Cup 2022 and the AFC Asian Cup 2023 will be announced in due course.”The AFC also suspended its elite club competition, the Asian Champions League (ACL), in early March because of the virus.Qatar will be the regional hub for matches in West Asia when the ACL resumes on Sept. 14. Malaysia was named the centralized hub in East Asia with matches in the region due to restart in October.  Topics :last_img read more